Sentence examples for a decreased capability from inspiring English sources

The Bcl-x-null cells exhibited a decreased capability to invade under conditions mimicking hypoxia; in contrast, when the same cells were assayed in normal conditions, their invasiveness was comparable to Bcl-x proficient cancer cells.

One of the important biochemical differences between normal and cancer cells is a decreased capability of cancer cells to buffer high ROS levels.

With this in mind, we hypothesize that the protective effect of a P1[B] deletion genotype of the 12p13.31 CNV may be due to a decreased capability of individuals with this variant to express SLC2A3.

With aging, a reduction in sympathetic responsiveness is characterized by: 1) a lower number of catecholamine receptors in peripheral target tissues; 2) a decline of heat shock proteins that increase stress resistance; and 3) a decreased capability of catecholamines to induce heat shock proteins.

Importantly, our observation of a decreased capability of the cKO mice during the acquisition phase in the radial arm maze, and the observations we make in the seizure-prone slice preparation could also be due to a loss of glutamatergic signalling, by the targeting of " Vglut2- only" cells and the glutamatergic, instead of the dopaminergic, component of the glutamate/DA cophenotypic cells.

Parthenogenetically activated oocytes of importin α7ΔIBB/ΔIBB females with successful pronuclear formation showed a markedly decreased capability to develop into two-cell embryos (Tab. 2).

Therefore, it is likely that the individual with the variants of C421A A allele and/or G34A A allele may have decreased capability to exclude the carcinogens and thereby becomes susceptible to carcinogenesis.

MarR family transcriptional regulator has the function of regulating the oxidative stress response; therefore, deletion of MarR coding genes may result in an increased bacterial sensitivity to oxidative and aerobic stress, decreased capability of intracellular survival in macrophages, and reduced virulence [ 22].

We have screened a transposon mutant library of R. equi for mutants with decreased capability to prevent phagolysosome formation.

Stromal cells over-expressing NICD1 reduced M-CSF production and enhanced RANKL and OPG production, resulting in the decreased capability of these cells to support osteoclastogeneis (Yamada et al., 2003).

This implies decreased capability of the 5'-end promoters in initiating transcription after treatment with alcohol.