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This can be controlled by first monitoring the decrease in surface stress amplitude due to the increased probe coverage and therefore a decreased availability in gold area and then evaluating the surface stress pattern change due to comparative adsorption of chloride ions in solution and the negatively charged oligonucleotide phosphate backbone [22].
However, with a decreased availability of the resource over time, and an increased consumer population, diet switching to alternative prey by the consumer often occurs, resulting in complex trophic interactions [7], [10].
This raises the possibility that binding of methyltransferases to expanded PABPN1 accumulated in nuclear inclusions leads to a decreased availability of the enzymes in the nucleoplasm, which may in turn reduce the methylation status of other cellular targets.
In sickle cell anemia more adhesion molecules are produced owing to a decreased availability of NO [ 20].
Any situation resulting in a decreased availability of T4 to the fetal brain is potentially adverse for neurodevelopment.
Various authors have described a decreased availability of vitamin K (both K1 and K2) in patients with chronic kidney disease (CKD) [ 19– 24].
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In vitro analysis using a full-length CPO demonstrated that hemin addition resulted in a 99% decreased availability of CPO in the mitochondria (Susa et al. 2002).
Exposure to hypobaric hypoxia, a condition involving decreased availability of oxygen is known to be associated with oxidative stress, neurodegeneration and memory impairment.
More importantly, IL-2 did not significantly increase the numbers of Treg precursor cells, suggesting that the Treg cell developmental defect can not be exclusively referred to a proliferation defect caused by decreased availability of IL-2.
There are several in vitro and in vivo data suggesting a direct link between the decreased availability of vitamin K and vascular calcification, based on the role of this vitamin in the activation of MGP [ 9, 18].
We suggest that this is the basic disorder causing proximal tubular dysfunction, either through a diminished resorptive area and decreased availability of transport proteins or through increased backleak of solutes from the proximal tubular cell.
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