The Arabidopsis rpn10 mutant shows a decreased sensitivity to auxin and is highly sensitive to exogenous application of ABA [ 51].
The decrease in resorption represents a decreased sensitivity to systemic stimuli, such as PTH, and reflects an interaction between hormonal and physical forces at the cellular level.
Substitution of key residues inside these strands with hydrophobic amino acids results in a decreased sensitivity of the protein to chemical and/or thermal denaturation.
This is often due to the emergence of clones expressing mutant forms of Bcr-Abl, which exhibit a decreased sensitivity towards inhibition by imatinib.
A decreasing sensitivity of the turbulent-flame speed to increases in turbulence intensity is found to occur beyond turbulence intensities of approximately 2.5 times the laminar-flame speed.
Nonetheless, our study was consistent with previous findings of unchanged Treg numbers in the skin after exposure of Cbl-b−/− mice to UVB and a possible higher cytotoxic activity of CD8+ T cells by a decreased sensitivity to Treg-mediated immunosuppression6.
In a DSC, a lower rate leads to a lower heat flux to the sample, and thus a decreasing sensitivity [1, 39].
The result is a decreased sensitivity to nondepolarizing neuromuscular blocking agents and a requirement for larger doses to observe the same effect.
One limitation of our study is the use of surface coils for MRI acquisitions, resulting in a decreasing sensitivity from the cranial vertex to the skull base.
Multiple studies have shown that endothelial dysfunction occurs in sepsis, as evidenced by a decreased sensitivity to vasoconstricting but also vasodilating agents.
