The phrase "a decrease of function" is correct and usable in written English.
It can be used in contexts discussing a reduction in the performance or capability of a system, process, or biological function.
Example: "The patient exhibited a decrease of function in their motor skills following the injury."
Alternatives: "a reduction in function" or "a decline in function."
This can be described in text as an inactive enzyme instead of a decrease of function relative to wildtype as in the below example sentences: "Replacement of Trp-125 or Trp-175 with arginine leads to a nonactive enzyme".
For example, [T]hey said I had kind of an ADD process where, you know, when I'm concentrating, especially on, you know, something that's relatively mundane, there's a decrease of function in the front part of my brain, so that it lends itself to having more difficulty with staying on task with boring things (C014).
On the controlateral kidney a decrease of renal function (p < 0.05) was observed.
Furthermore, our findings demonstrate that the presence of depressive symptoms does not influence a decrease of kidney function.
Hypothyroidism induces a hypodynamic state of the circulatory system, which would result in a decrease of renal function and particularly of glomerular filtration rate [ 1].
A continuous loss of podocytes due to apoptosis leads to glomerulosclerosis, a decrease of kidney function and finally to the dependence of dialysis.
In depressed patients there is generally a decrease of sexual functioning.
In addition, an excessive dose of 50 mg/kg resulted in a decrease of cognitive functions below control levels, indicating a detrimental effect of MB [ 84].
The G118A substitution led to a drastic decrease of function, as shown by a complementation test in the Zn-hypersensitive mutant zrc1Δ.
In amphibians, functional diversity declined dramatically towards OP indicating a decrease of their ecological function.
To calculate a decrease of the barrier function Ψ ( v ) during an inner iteration it is standard to consider a decrease as a function of α defined by f : = Ψ ( v + ) − Ψ ( v ).
