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Guidelines and their incorporation in a DSS are part of a general trend towards rationalization of medicine in the Western world and one of the general implications of rationalization processes is a decrease in variation.
The results showed here are in accordance with previous comparisons using allozyme variability [ 19, 28], microsatellites [ 10, 29] and mitochondrial DNA [ 30], where a decrease in variation was observed in Australian populations, probably due to a bottleneck followed by a population expansion after the initial founder event.
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The increase of genetic variation in Bythotrephes body length was associated with a decrease in maternal variation that together resulted in increased heritability, despite a concomitant increase in environmental variation.
Although it is less clear how phenotypic variation will respond to the same processes, population genetics theory suggests that a decrease in phenotypic variation should also be evident [ 50], especially in the case of morphological traits [ 51].
As the number of individuals increases, we can observe an increase in the predictability and a decrease in the variation of predictions for each trait (Fig. 4).
We also observed a decrease in the variation spread of incline in cambial cells over time.
Using method bpMAF to select LDP SNPs also resulted in a decrease in the variation in imputation accuracy across SNPs compared to the bpEQ method.
A problem in phenotyping is the lack of genetic diversity in cultivated plants, which underwent heavy selection during domestication (8 11), causing a decrease in genotypic variation.
Both patient groups with normal myocardial function and with impaired myocardial function showed significant fluid responsiveness (that is, a decrease in PP variation after fluid loading) [ 1].
The assumption is that a decrease in genetic variation and a lack of exchange between isolated populations increase the likelihood of extinction by reducing the population's ability to adapt to changing environmental conditions [ 2].
A decrease in genetic variation in the direction of colonization has been documented for many organisms (e.g. Prugnolle et al. 2005 for humans; Williams et al. 2007 for Brazilian peppertrees).
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