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With increased cultivation times, RNAs encoding cardiac calsequestrin increased [33], [36], but a decrease in transcripts encoding atrial natriuretic factor (ANF) was observed [37] (Figure 2E).
We observed a decrease in transcripts that include exon 8, and an increase in transcripts that skip exons 7 and 8, relative to APP transcripts from the control cells (Figure 6C).
Inhibition of PfSpdSyn resulted in a decrease in transcripts for proteins involved in methionine recycling.
This is consistent with the suggestion that α-synuclein monomer levels may be sustained, despite a decrease in transcripts, through a decrease in its degradation via CMA.
We demonstrate that reduced Smn levels are correlative with a decrease in transcripts implicated in ribosome, rRNA binding, ubiquitin and oxidative phosphorylation.
In contrast, Portillo et al. [ 56] reported a decrease in transcripts of the PR-1 precursor in giant cells collected from tomato infected with M. javanica by LCM as measured using qRT-PCR.
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In agreement with the disorganization of the mitochondrial complex activities in DIO old rats, there was a decrease in transcript levels of PGC1α, a transcriptional co-activator playing a multifaceted role in the regulation of mitochondrial energy metabolism and biogenesis.
The microarray data suggest a decrease in transcript levels after day 15 for most of the genes studied.
Furthermore, this decrease in E2F target gene expression was accompanied by a decrease in transcript levels of the adipocyte differentiation marker aP-2 (Figure 7C).
If CF2 has a role as a repressor in the IFM, then an increase in function should cause a decrease in transcript levels of genes encoding structural proteins.
Such experimental conditions could provoke a stress and explain that for several genes (atpA and atpG, for example) a decrease in transcript abundance was temporarily observed at 06 30.
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