The phrase "a decrease in transcriptional" is correct and usable in written English.
It can be used in contexts discussing gene expression, molecular biology, or any situation where transcriptional activity is relevant.
Example: "The study revealed a decrease in transcriptional activity in the affected cells."
Alternatives: "a reduction in transcriptional" or "a decline in transcriptional".
This promoter variant disrupts a Sp1/Sp3 transcription factor binding site and causes a decrease in transcriptional activity in lung fibroblast cells [22], [23].
The low signal for FVIII INS was not due to a decrease in transcriptional initiation.
This active state of the endothelium is reflected by our study, with nearly 20-times more genes upregulated from E7 to E10, followed by a decrease in transcriptional activity after E10.
In transitioning to the larval stage, an increase in many metabolic functions and a decrease in transcriptional regulation were observed.
The fewer number of significant genes found for Trout Lodge relative to Hofer may indicate a decrease in transcriptional activation for this susceptible strain.
For example, knockdown of PIGB resulted in a decrease in transcriptional activity of Elk-1/SRF, AP1, NFκB, and Myc/MAX in SU86 cells, indicating a down-regulation of these signaling pathways.
In agreement with the disorganization of the mitochondrial complex activities in DIO old rats, there was a decrease in transcript levels of PGC1α, a transcriptional co-activator playing a multifaceted role in the regulation of mitochondrial energy metabolism and biogenesis.
Avicins dephosphorylate Stat3 in a variety of human tumor cell lines, leading to a decrease in the transcriptional activity of Stat3.
Pre-treatment of cells with avicin D resulted in a significant decrease in both the constitutive as well as IL-6 induced Stat3-luciferase activity (Fig. 4A), suggesting a decrease in the transcriptional potential of Stat3.
Interestingly, the mutant GLI3 proteins had significantly decreased capabilities to induce the luciferase signal, suggesting that indeed the misregulated localization of mutant GLI3 leads to a decrease in its transcriptional activity (Fig. 5a).
Avicin D treatment resulted in dephosphorylation of both constitutive and induced Stat3 in a time and dose-dependant manner, leading to a decrease in the transcriptional activity of Stat3.
