Sentence examples for a decrease in therapeutic from inspiring English sources

A decrease in therapeutic doses of PNP-GDEPT could also lower the total Fludara required; this is important given its potential immunosuppressive effects.

In contrast, a gradual decrease in therapeutic response was observed with 10 mg kg-1 cisplatin.

A gradual decrease in therapeutic response was detected using growth delay and clonogenic cell survival during repeated drug treatment.

We hypothesized that a decrease in proteinuria by using therapeutic interventions is associated with decreased urinary KIM-1 levels.

Thus, a decrease in the size of therapeutic antibodies along with the development of a new approach to deliver them to poorly accessible CNS tumors may help to overcome the existing difficulties.

However, the association of a decrease in ACPA levels with therapeutic response has been variable [ 3– 13].

In fact, redox-dependent generation of the active form of drug from the "pro-form" distinguishes this therapeutic approach from traditional EPs such as curcumin, and results in a decrease in clinical side effects at therapeutic concentrations, e.g., lack of reaction with other thiols such as glutathione (GSH), which can result in lowering GSH and inducing oxidative stress in normal cells.

In fact, redox-dependent generation of the active form of drugfrom the "pro-form" distinguishes this therapeutic approach from traditional EPs such as curcumin, and results in a decrease in clinical side effects at therapeutic concentrations, e.g., lack of reaction with other thiols such as glutathione (GSH), which can result in lowering GSH and inducing oxidative stress in normal cells.

12) A decrease in blood pressure that requires therapeutic intervention is a HRE.

Some JAK2 inhibitors, including TG101348 and CYT387, improve bone marrow fibrosis in JAK2V617F BMT mice, but unfortunately they also produce a decrease in the hematocrit in the therapeutic dose range in mice.

Animal studies documented a decrease in global toxicity and an increase in therapeutic effectiveness of chemotherapy when combined with PHY906.