Exact(7)
In an in vivo study, pentobarbital suppressed the expression of TNF-α mRNA and its proteins, which may result from a decrease in the activities of nuclear factor-κB and activator protein 1 and the reduction of the expression of p38 mitogen-activated protein kinase by pentobarbital [ 125].
Administration of bromobenzene caused significant changes, including decrease in the mitochondrial respiration and P/O ratios, an increase in lipid peroxidation and protein oxidation, and a decrease in the activities of antioxidant enzymes (catalase, superoxide dismutase, glutathione reductase, and glutathione peroxidase) in mitochondria with significant histopathological changes in the kidney.
A recent study reported that lipid peroxidation leads to a decrease in the activities of ETC complexes III and IV [37], and it is possible that the decreases in complex IV activity in previous studies was due to lipid peroxidation secondary to very large increases in membrane unsaturation.
Growth on ammonium causes a decrease in the activities of the enzymes used to assimilate less favourable nitrogen sources.
A decrease in the activities of Mn and CuZn superoxide dismutase isoenzymes and catalase has been found in the brain, heart, liver, and kidney of aging mice (Gupta et al., 1991; Navarro et al., 2004).
As discussed above, increased PI synthesis causes a decrease in PA content, which results in the Opi1-mediated repression of UASINO-containing genes and a decrease in the activities of the CDP-DAG pathway enzymes (Iwanyshyn et al. 2004).
Similar(53)
A decrease in the activity of G-Rx would further decrease the concentration of ascorbic acid.
Extensive trypsin digestion resulted in a marked decrease in the activity of the transporter.
Losey said there's been a decrease in the lethality of LRA activities attributable to U.S. and partner nation efforts.
This decrease in specific intrinsic demand could be due to a decrease in the proportion of highly metabolically active tissues (the midgut) or to a decrease in mitochondrial activity in individual cells.
We found that decreased intrinsic demand, mediated by a decrease in the proportion of highly metabolically active tissues in the fifth instar, along with a decrease in the specific mitochondrial activity, contribute to the hypoallometric scaling of metabolic rate.
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