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It exhibits the tradeoff between "sensitivity" and "specificity" i.e. an increase in "sensitivity" will be accompanied by a decrease in "specificity".
However, this could possibly lead to a decrease in specificity as the surveillance system could potentially falsely signal when there was an increase in other causes of influenza-associated hospitalisations, e.g. respiratory syncytial virus.
These characteristics are needed to determine how an increase in sensitivity is counterbalanced by a decrease in specificity.
13 Unfortunately, an increase in the sensitivity of child abuse detection would lead to a decrease in specificity.
It is recognised that the increase in sensitivity of lower threshold PRL is accompanied by a decrease in specificity.
The experienced radiologists can be mislead by the enhancement pattern of CAD, resulting in a decrease in specificity.
Similar(36)
Lastly, one study [ 20] that used the HDS with standard cut-off criterion found that by including only those in the sample who were viruologically suppressed, sensitivity and overall classification accuracy were raised (24%to66%66 %, and 57 % to 61%%, respectively), although this was associated with a decreased in specificity (92 % to 50%%).
This argument is in agreement with our CL2 data showing similar neuronal specificity with slightly reduced uptake, and with our CL1 coat data, which shows a decrease in neuronal specificity with the removal of one of the carboxyl groups and the addition of a piperazine with two positive charges.
In contrast to these mutations that led to a decrease in the specificity of the ERK2-Ets interaction, the modeling also allows for a prediction of potential mutants that might improve specificity.
Thus, there was indeed a decrease in stimulus specificity.
We identified a RIN threshold beyond which we observed a decrease in assay specificity and sensitivity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com