The phrase "a decrease in responsiveness to" is correct and usable in written English.
It can be used in contexts discussing changes in behavior, reactions, or sensitivity to stimuli or situations.
Example: "The study found a decrease in responsiveness to the medication over time, indicating a potential need for dosage adjustment."
Alternatives: "a reduction in sensitivity to" or "a decline in reaction to".
In several cell types, there was a decrease in responsiveness to stimulation by certain cytokines (Fig. 2A).
Anhedonia, a core symptom of depression, was modelled by inducing a decrease in responsiveness to rewards reflected by a reduced consumption and/or preference of sweetened solutions.
This is consistent with findings in Drosophila showing that prolonged exposure to an odorant induces structural changes in the antennal lobes correlated with a decrease in responsiveness to that odorant [47].
This could be the result of basic processes such as habituation (non-associative, elemental learning resulting in a decrease in responsiveness to a prolonged or repeatedly experienced stimulus [33]) or sensory adaptation, at the receptor level [34].
Anhedonia, a core symptom of major depression in humans, is modeled by inducing a decrease in responsiveness to rewards, as reflected by reduced consumption or preference for sweetened solutions [ 31].
More than 30% of RA patients, however, have been estimated to demonstrate a decrease in responsiveness to GC therapy within 3 to 6 months from initiation of treatment [ 64].
This demonstrates that SRM1648 induced a decrease in responsiveness of smooth muscle to NO, rather than a decrease in endothelial NO production and/or bioactivity, and that SRM1648 impairs the NO signaling pathway upstream of activation of cGMP-dependent protein kinases.
Food supplementation results in a decrease in responsiveness of female fireflies (Photinus ignitus) to simulated male flashes [ 24], whereas food restriction results in lower responsiveness and reduced probability of mating in female cockroaches (Nauphoeta cinerea) [ 25].
For example, a decrease in responsiveness of the small-spiking neuron of rare ECB(E) males to Z12 14 OAc may alter the firing ratio relative to the large-spiking neuron in a way that allows the ACB blend to mimic the ECB(E) blend [22].
GPCRs and membrane trafficking mechanisms that are expressed in the larval stages are candidate regulators of competence and metamorphosis, and indeed, exposure of precompetent larvae to an inductive cue results in habituation or a decrease in responsiveness that delays settlement [ 13].
Finally, repeated exposure to violent media cues lead to reduced psychological and affective arousal by violent media stimuli that is related to a decrease in emotional responsiveness to real-life violence and suffering".
