Sentence examples for a decrease in phosphatase from inspiring English sources

Moreover, there are reports suggesting HOTAIR might also control DNA methylation, as its depletion in Hep-2 cells lead to a decrease in phosphatase and tensin homolog (PTEN) promoter methylation [ 79].

In order to investigate if the increased phosphorylation of tau was due to a decrease in the phosphatase activity of neurons, we investigated the effect of QA on phosphatase activity using pNPP as a substrate.

A decrease in alkaline phosphatase during winter has been reported earlier in black bears [ 23], and may reflect decreased bone turnover.

Arif et al. (2014) recently found a decrease in protein phosphatase 2A (PP2activityity associated with abnormal hyperphosphorylation of tau in brain of ALS/PDC patients.

Previous studies identified a single point mutation (D239N) that results in a 4000-fold decrease in phosphatase activity in human PP2Cα (Jackson et al. 2003).

The effects of DEX on LTP and LTD were correlated with an increase in the autophosphorylation of Ca2+/calmodulin-dependent protein kinase II at threonine-286 and a decrease in the protein phosphatase 1 expression.

In one patient (Pt 11), the rise in PSA was associated with a decrease in serum alkaline phosphatase and bony pain.

We propose that a decrease in major tau phosphatases (PP2A, PP1 and PP5) is a mechanism for this increased in tau phosphorylation in neurons exposed to QA at pathophysiological concentrations.

There was less gelatinase B/matrix metalloproteinase-9 expression in the Nx-MP group, which was not associated with a decrease in tartrate-resistant acid phosphatase (TRAP) staining in the chondro-osseous junction.

In addition, obese-prone rats treated with HF-diet exhibit an upregulation of TLR4 in the gut wall and a decrease in the intestinal alkaline phosphatase activity.

Inversely, reduction of TBP levels to 50% by inactivating one of its alleles in chicken DT40 lymphoid cells results in a decrease in the expression of cdc25B phosphatase.