Sentence examples for a decrease in hepatic from inspiring English sources
A decrease in hepatic ATP content was also observed in MCD-fed mice.
High doses of I3C, probably never achieved after consumption in humans, exhibit a dose-dependent toxicity including a decrease in hepatic reduced glutathione and severe neurological toxicity in mice [34].
The decrease in plasma IGFBP-3 was not accompanied by a decrease in hepatic or renal IGFBP-3 mRNA, suggesting that in this case, plasma IGFBP-3 protein levels are posttranslationally regulated or are derived from tissues other than liver or kidney.
These observations suggest a decrease in hepatic activity induced by radiation exposure.
In contrast, a decrease in hepatic TfR1 and Fpn-1 protein amount was evident at later time points.
There was a decrease in hepatic Hmgcr activity observed with the higher dose of EPA-EE (Fig. 7A).
In wild-type and db/db mice, adenoviral overexpression of RNF20 markedly suppresses FASN promoter activity and reduces the level of hepatic triglycerides, accompanied by a decrease in the hepatic lipogenic program.
However, data regarding the phospholipid export pump (MDR3) are not conclusive, but some suggest a decrease in its hepatic expression in experimental inflammation models [ 47, 49].
The myofibroblast differentiation of HSC is associated with a decrease in total hepatic levels of retinyl palmitate [ 116], the predominant storage form of vitamin A in rat HSC, whereas levels of retinol are increased together with CRBP-1 levels [ 117].
While the physiological relevance of a decrease in total hepatic mTOR protein abundance is difficult to interpret, it may limit the maximum capacity of downstream events such as lipogenesis.
For example, the TLR2 deficiency causes a reduction in macrophage infiltration but also induces significant suppression of autophagy associated with a decrease in the hepatic expression of tumor necrosis factor, interferon gamma, and [C-X-C motif] ligand 2. This enrichment in M2 macrophages in turn promotes hepatocarcinogenesis [ 83].
