The phrase "a decrease in genomic" is correct and usable in written English.
It can be used in contexts discussing changes or reductions related to genomic data, sequences, or characteristics.
Example: "The study revealed a decrease in genomic diversity among the populations over the last decade."
Alternatives: "a reduction in genomic" or "a decline in genomic".
A decrease in genomic PDGFRα dosage, as shown in heterozygous PDGFRα+/− mice [49], resulted in impaired remyelination after myelin damage to the CNS [50].
However, for the Thermoprotei there was no clear trend for the indicators as a whole and for genomic GC content there appeared to be a decrease in genomic GC content from LGT genes to non-LGT genes.
Modifications to DNA methylation occur on a genomic- and gene-specific level in colorectal neoplasia: a decrease in genomic DNA methylation (hypomethylation) (11) is accompanied by an increase in methylation of CpG islands in the promoter regions of many tumor-suppressor genes (hypermethylation) (12, 13).
A decrease in viral genomic RNA was detected by RT-PCR after addition of Triton X-100 to sucrose-cushion purified virus and incubation at 37°Cfor 1 h, indicating an RNase in this preparation was able to access viral RNA after lysis (Fig. 3B).
Simulations of bisulfite-converted DNA show a decrease in identifying genomic positions uniquely in 6% of 36 nt reads and 3% of 70 nt reads.
Premature expression of miR-UL112-1 miR-UL112-1 miR-UL112-1esulteduring significant decrease in genomic viral DNA levels, suggesting a functional role for miR-UL112-1 in regulating tHCMVxpressinfectionnes involved in viresultedination.
This regulatory loop seems to be highly effective in vivo as in the DGCR8 heterozygous knockout mouse the protein levels of DGCR8 are only modestly reduced despite a 50% decrease in genomic DGCR8 [ 134].
In addition, interpreting the functional effects of variants that fall outside protein-coding regions remains very difficult, and discriminating between mutations underlying cancer progression ('drivers') and changes resulting from a general decrease in genomic stability ('passengers') requires variants in many cancers to be assayed to look for those present multiple times.
When we stratified our population using the cutoff value used by Friso et al, we observed a 26% decrease in genomic DNA methylation between CC and TT subjects in those with serum folate values <12 nmol/L, although the number of subjects was too small (12 CC and 2 TT) to allow a statistical comparison.
When low-accuracy imputation was applied in training and prediction animals we observed a decrease in accuracy of genomic evaluation.
As summarized in Table 2, Dnmt1 haploinsufficiency did not cause a corresponding 50% decrease in genomic 5-mdC content, but an obvious reduction in 5-mdC level was consistently seen among the three age groups examined.
