Exact(1)
Zhuravleva et al. did observe a decrease in fragmentation rate in the 2005 2010 time period than 5 years prior, while we observe an increase in the second 5 year span, due to the fact that we assess changes between successively degraded classes as degradation, whereas with IFL degraded forests remain in the same class and thus secondary degradation is not entirely accounted for.
Similar(59)
Sitagliptin treated rats demonstrated a decrease in DNA fragmentation and apoptosis.
NAVA showed a normal percentage of REM sleep with an important decrease in fragmentation.
A decrease in muscle metabolism during myofiber fragmentation and cellularization would account for much of this depression.
In human cells, treatment with the chemical uncoupler FCCP causes an increase in oxygen consumption and a decrease in ATP generation, provoking mitochondrial fragmentation and the appearance of donut-shaped mitochondria [ 43].
Such fragmentation can have potential genetic consequences, including loss of genetic variation within fragmented stands and a decrease in gene flow between isolated fragments (Young et al., 1996).
In summary, we show that mitochondrial fragmentation and a decrease in mitochondrial area (as a read out of decrease in mitochondrial volume correlate with age and are likely to participate in the degeneration of body wall muscles.
Our group recently reported that a Caesalpinia spinosa-derived fraction enriched in hydrolyzable tannins induces a cytotoxic effect on leukemia cells (K562), apoptosis with mitochondria membrane potential (MMP) loss, DNA fragmentation, and a decrease in clonogenic capacity [ 12].
Hence, an increase in mitochondrial fragmentation and a decrease in mitochondrial volume with age are likely to be causal in the age-dependent decrease in mitochondrial activity that has been observed in C. elegans as well as other organisms [ 22- 26, 26].
Ultimately, apoptosis results in fragmentation of the DNA, a decrease in cell volume, and phagocytosis of the apoptotic cell by nearby phagocytes.
In addition, in both experimental groups, fluoxetine induced several hallmarks of apoptosis in the liver, including a decrease in Bcl-2 expression and increased DNA fragmentation.
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