The phrase "a decrease in differentiation" is correct and usable in written English.
It can be used in contexts discussing changes in variety, uniqueness, or specialization in a particular field or subject.
Example: "The recent trends in the market indicate a decrease in differentiation among competing products, leading to consumer confusion."
Alternatives: "a reduction in differentiation" or "a decline in differentiation".
Drug resistance has been associated with expression of various pluripotency markers, including NANOG, OCT4 and SOX2, since these genes typically lead to a decrease in differentiation status [68].
The most common characteristics of a senescent phenotype are a gradual decrease in the proliferation potential and a decrease in differentiation capacity [19] [20].
Generally, HCC progression can be defined by a decrease in differentiation, the loss of tissue-specific gene expression, acceleration of cell proliferation and, ultimately, metastasis [ 3].
Loss of SHH signaling has been associated with a decrease in differentiation markers such as SOX9 and Brachyury in NP cells as well as a reduction in proteoglycans.
No gross alterations in brain structure of RSK2 mutants are evident, although a decrease in differentiation of cortical radial progenitors into neurons was observed in mice, which indicated a function of RSK2 in neurogenesis (Dugani et al., 2010).
Given that stocking practices has traditionally been executed at the administrative regional scale, we observed a decrease in differentiation among populations within regions and an increase in regional genetic differences due to stocking.
Thus, the reduction in the weight of the JAG1 IL4 gene interaction in the MS patient network indicates a decrease in Th2 differentiation.
Interestingly, we found a decrease in the differentiation of DA precursors into TH+ neurons in Dkk1+/− embryos compared with Wt littermates (Figure 3E).
Altered expression of Collagen I and II may also indicate a decrease in chondrocyte differentiation, which is hallmarked by high expression of collagen II and low expression of collagen I.
Furthermore, our results showed a decrease in genetic differentiation among donor and stocked populations.
This causes a decrease in osteogenic differentiation and a reduction in BMP-2 and BMP-4 expression [ 1, 5].
