Yet the significant fear × year of survey interaction term showed that the role of fear of a positive test result had decreased in differentiating between those who had never been tested and those who had; so, although there is evidence that its role is diminishing, fear of a positive test result remained particularly important in explaining differences in testing behaviours.
Transcript levels of the respective inner and outer mitochondrial membrane subunit proteins succinate dehydrogenase complex, subunit A (SDHA) and translocase of the outer mitochondrial membrane 20 homolog (yeast) (TOMM20) revealed relatively uniform expression during lens cell differentiation; however, the protein level was decreased in differentiating lens fiber cells.
The fact that RHAU deletion leads to no apparent change in undifferentiated spermatogonia, but significant decreases in differentiating cells, suggests possible abnormal cell proliferation and/or cell death during spermatogonia differentiation.
These transcripts of the cluster were also observed preferentially in ES cells, but notably, they decreased in differentiating cells [51], suggesting the role of the cluster in pluripotency of ES cells.
Other studies have reported that, in contrast to the transcript levels analyzed in the present study, p62/SQSTM1 protein levels actually decreased in differentiating lens fiber cells (Wignes et al. 2013; Basu et al. 2014b) raising the possibility that posttranscriptional and/or translational regulatory mechanisms could operate to regulate p62/SQSTM1 levels in lens cells.
Similarly, cyst regression was defined as a decrease in score, which did not differentiate those that resolved completely.
107, 112 However, during aging, preadipocytes experience a decrease in their potential to differentiate and replicate.
Typical phenomena associated with stem cell aging are a decrease in the potential to differentiate and to proliferate (Pollina & Brunet, 2011).
Moreover, in addition to a decrease in the proportion of NR4A2+ precursors differentiating into TH+ DA neurons (25% decrease in the Wnt5a mutants compared to WT), we found that NR4A2+ DA precursors were generated in excess by E12.5 (47% in the Wnt5a mutants compared to 39% in WT).
Prolonged neural differentiation in the presence of low FGF2 (5 ng/ml) resulted in a higher cell density in the culture but led to a decrease in the number of cells that differentiated into neurons (Fig. 4c).
