The phrase "a debilitating effect on" is correct and usable in written English.
It can be used to describe the negative impact or harm that something has on a person, group, or situation.
Example: "The disease had a debilitating effect on her ability to work, forcing her to take a leave of absence."
Alternatives: "a crippling impact on" or "a harmful influence on".
He feared once or twice that his settled relationship with Jörn might have a debilitating effect on his gift for tainted love songs, the yearning, nuanced ballads, one part Morrissey, one part Mahler, with which he made his name.
This has a debilitating effect on society.
The No Child Left Behind Act of 2002 had a debilitating effect on arts education.
Legitimate measures to curb funding of and money-laundering by terrorist organisations often have a debilitating effect on NGOs.
I can state, as a former trucker, that a longer workday does have a debilitating effect on safety.
"This undermines confidence in the Palestinian Authority's capacity to function, which has a debilitating effect on investor confidence.
Tremlett was delighted and even a little surprised to have been selected for the Ashes tour in the first place after a low-key season with Surrey but he admits the relentlessness of year-round touring may have had a slightly debilitating effect on some of England's more senior players.
"I do not believe," Pearl added earlier this week in an interview in a Manhattan law office, "that he would knowingly engage in a strategy that has such a cruel and debilitating effect on so many lives".
But Vanishing of the Bees, made by the independent filmmakers George Langworthy and Maryam Henein, suggests that long-term, low-level exposure to these compounds may be having a sub-lethal but debilitating effect on honey bees.
The most debilitating effect, one investigator said, has been "a paralyzing fatalism," a malaise brought on by an alien presence that almost seems alive.
