To understand the regulatory function of SHP with regard to miR-206 gene expression, we determined the putative transcriptional initiation site of miR-206 and also its full length primary transcript using a database mining approach and RACE.
More than 30 defensins in human and mouse [11] and 14 β defensins in birds [12], [13], [14] were identified, but only 3, 2 and 2 β-defensin genes were respectively found in zebrafish, Fugu and Tetraodon by using a database mining approach.
The FP-tree data structure and algorithm were originally developed as a database mining tool [ 31] to identify frequent combination of patterns in databases.
FJW carried out experiments, including all database mining, phylogenetic studies, permutation tests, and sequence alignment analyses.
A total of 295 RGHs were identified from 424,545 switchgrass ESTs with an EST database mining approach.
The first involves gathering data from disparate sources, integrating it into a universally accessible database, mining it for insights, and then recommending concrete actions related to strategy and marketing.
We present a program for database mining of the exponentially increasing number of receptor-ligand complexes, in particular, performing a pocket similarity search and extracting meaningful fragments that can be useful for Fragment-Based Lead Discovery.
To determine the transcriptional control of miRNAs, we set up a computational and database mining approach.
The omega-3 FAD-type genes in G. hirsutum (AD1 allotetraploid), G. herbaceum (A1 diploid), and G. raimondii (D5 diploid) were cloned and sequenced using a combination of database mining, degenerate primer-based PCR screening, genome resequencing, and gene-specific PCR-based cloning, as described in the Methods.
Different fingerprints are used to facilitate a similarity step for database mining, followed by a diversity step to assemble the final library.
After decades of failed efforts that relied on classic biochemistry and membrane protein purification, Vamsi Mootha, a Harvard Medical School HMSS) associate professor of systems biology, and his colleagues have discovered, through a combination of digital database mining and laboratory assays, the linchpin protein that drives mitochondria's calcium machinery.
