Sentence examples for a cyclic nucleotide from inspiring English sources

Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide.

Epac1 is a Rap-specific guanine-nucleotide exchange factor (GEF) which is activated by the binding of cAMP to a cyclic nucleotide monophosphate (cNMP -binding domain.

Although several putative heat sensors have been proposed, including a cyclic nucleotide gated calcium channel (CNGC), two unfolded protein sensors, and H2A.Z-containing nucleosomes,3 it is unclear whether these potential sensors-mediated mechanisms are also responsible for the H3K27me3 demethylation-mediated thermomemory.

In addition, a cyclic nucleotide binding domain (cNBD) immediately C terminal to the pore domain is thought to contribute to the stabilization of the tetrameric structure [6].

It was shown that cAMP level rises during recovery from Si-starvation and that the activity of a cyclic nucleotide phosphodiesterase increases upon addition of silicic acid in C. fusiformis [54], [55].

Voltage clamp studies (two-electrode configuration) demonstrated that AtCNGC1 is also a cyclic nucleotide gated channel.

A cyclic nucleotide-independent protein kinase has been isolated from Drosophila melanogaster by chromatography on phosphocellulose and hydroxylapatite followed by gel filtration and glycerol gradient sedimentation.

Schünke, S., Stoldt, M., Lecher, J., Kaupp, U. B. & Willbold, D. Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel.

The successful construction of a cyclic nucleotide-gated KcsA K+ channel suggests that it should be possible to produce channels that will respond to novel ligands.

In vertebrate olfactory receptor neurons (ORNs), the odorant-triggered receptor current flows through two distinct ion channels on the sensory cilia: Ca2+ influx through a cyclic nucleotide-gated (CNG) channel followed by Cl− efflux through a Ca2+-activated anion channel.

In addition to the domain architectures involved in the characterized functional groups, a cyclic nucleotide-binding domain was also fused to various domains involved in pyridine nucleotide-disulfide oxidoreductase, acetyltransferase, thioredoxin reductase, glutaminase, rhodanese, ferredoxin, and diguanylate cyclase, implying the versatile functions of cyclic nucleotide-binding proteins.