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As a sensitivity analysis, we tested the prognostic value of LIS in two 'severe ARDS' subgroups as defined as (1) LIS ≥ 3, a cut-point used to identify 'refractory ARDS' for consideration of possible rescue therapies; [11 13] and (2) PEEP values ≥ 10 cm H2O, a cutoff which has been associated with improved consistency in measurement of hypoxemia [24].
The ProteinProphet score of 0.5 was used as a cutoff, which corresponds to a false identification rate of 3.5% in iron chelation experiment and 5.3% in p160 co-immunoprecipitation experiment, respectively.
For the Web the two levels are more dissimilar and the distributions have a clear power law decay (with different exponents) up to a cutoff
However, this original method does not consider a cutoff, which we denote by the constant A(p), in the degree distribution.
For comparison, the degree exponents are obtained by the maximum likelihood method considering a cutoff, which is the term A(p) (see Method for details).
A score of 13 or greater was used as a cutoff, which has been indicated for to correlate well with serious postpartum depression [ 32].
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This led to the introduction of a flexible cutoff, which can be used as an alternative to a static one.
This analysis used the Total Difficulties score as a continuous variable, rather than using a clinical cutoff, which is not available across these sites.
Subsequently, if the mean Pearson correlation coefficient across all RNA-seq samples for a pair of transcripts in both alleles is lower than a defined cutoff (which we empirically set to −0.25), we combine each of these pairs into a single combined transcript.
Such country-specific baskets are distinct from the World Bank's oft-quoted "dollar a day" cutoff, which states that any reasonable basket around the world should cost $1.25 87pperper day per person (at purchasing power parity rates).
Therefore, we introduce a flexible cutoff, which takes this issue into consideration.
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CEO of Professional Science Editing for Scientists @ prosciediting.com