The phrase "a course of time" is correct and usable in written English.
It can be used to refer to a duration or passage of time, often implying a gradual process or development.
Example: "Over the course of time, we have seen significant changes in the industry."
Alternatives: "over time" or "throughout the years".
Mr. Ban was questioned on an agreement between Iran and the International Atomic Energy Agency that allows Iran to answer questions on its nuclear program over a course of time.
Hollywood's hunt for formulaic catharsis, and consequent departure into its own hyperbolic world, means that real romance - the ball-tearing, spine-chilling effect created by brutally large and vibrant orchestras over a course of time - is, for me, back alone in its proper space.
So what you're seeing within the Republican Party is, to some degree, all of those efforts over a course of time creating an environment where somebody like a Donald Trump can thrive".
At a very basic level, neural networks are best modeled as networks of binary automata that are on or off over a course of time.
These potent stressors may again, in a course of time, limit coping resources in already recognized refugees and influence their profiting from the treatment on a longer term.
Last yet not the least, the authors of this work have agreed to devise in a course of time a more advanced model on restraining HBV transmission through migration.
These studies should include more assessment moments and more detailed information on resettlement stress in a course of the time.
Accordingly, being benefited from both aspects, a large amount of oil is swept within a short course of time in the 7 m case.
Sub-lethal infection (0.1×LD50) allowed the monitoring of cytokine accumulation over a prolonged course of time.
It is striking that 20 of the 27 patients from the control group were referred to a gynaecologist in course of time.
The thought goes: If natural selection modifies a species enough, over the course of time a new species will inevitably emerge.
