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Quality of life (QOL) is a core outcome of palliative care, yet in African settings there is a lack of evidence on patients' levels of QOL.
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Pain IMMPACT recommends the use of NRS as a core outcome measure of efficacy in clinical trials of chronic pain treatments [ 38].
Patients' assessment of physical function (PF) is a core outcome domain of disease status in rheumatoid arthritis (RA)[ 1, 2].
The PGIC has been used in trials of chronic pain [ 17, 18] and recommended as a core outcome measure of global improvement [ 19].
44 The Patient Global Impression of Change (PGIC) scale 45 was recommended by IMMPACT for use in chronic pain clinical trials as a core outcome measure of global improvement with treatment.
The development of a core outcome data set of "salutogenically-focused" outcomes for intrapartum research has been recommended [ 12].
The presented study aims to develop a core outcome set consisting of a minimum of outcome measures deemed necessary for medical and therapeutic decision-making, which must be measured in all clinical trials and non-randomised intervention studies.
For example, the analyst could run a query to search for evidence to support a core outcome such as the effect of the CS or AP on increasing knowledge and skill of other care providers.
These meeting procedures were developed after consultation with key leaders of OMERACT – a core outcome group with over 20 years of experience in core outcome set development.
The instrumentation and measurement tools will include: This 11-point scale (0-10 where 0 is no pain at all, and 10 is the worst pain imaginable) is ommonly used in the assessment of pain [ 33], and is a core outcome measure in clinical rials of chronic pain patients [ 34, 35].
The development of a core outcome set in cystic fibrosis (CF) would help reduce the problem of ORB.
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