The phrase "a core negative" is correct and usable in written English.
It can be used in contexts discussing fundamental or essential negative aspects of a situation, argument, or concept.
Example: "In the debate about climate change, a core negative is the potential for irreversible damage to ecosystems."
Alternatives: "a fundamental negative" or "an essential negative".
3. Does the scandal reinforce a core negative perception about the candidate?
Among them, genes GATA-1 and PU.1 form a core negative feedback module to regulate the genetic switching between the cell fate choices of HSCs.
Many of these signals feed into a core negative feedback loop involving the transcription factor WUSCHEL (WUS) and the CLAVATA1/2/3 (CLV) signaling complex, which act within the meristem to balance stem cell maintenance and cell differentiation [ 5– 7].
Our knowledge on this mechanism is based on Drosophila, where it comprises two transcriptional loops: A core negative transcriptional feedback loop, driving self-regulating daily rhythms and a second interlocking feedback loop (Allada and Chung 2010).
At first, the CACGTG-type E-box element and its related sequences in the promoter region of XtPer1 were examined as a plausible core negative regulator in the circadian molecular loop [8].
Duration of untreated psychosis had a significant effect on core negative symptom score (P=0.04) and core negative symptom score also had a significant effect on social function score (P<0.0001).
These positive feedback loops are interlocked with the core negative feedback loop, a feature that is shared in animal clocks.
The document underlines unrest within the shadow cabinet with a number of frontbench MPs listed in the fourth "core negative group" including Lucy Powell at education and Maria Eagle, who was moved from her role in defence to culture.
Thus, in this study when we used a negative syndrome score derived from all sub-scales of the SANS, we found a stronger relationship with DUP than when we used only core negative symptoms in the analysis.
It will reinforce some core negative perceptions about Mr. Perry: that he is a bad debater, that he is a lightweight, and that he is someone who is not quite ready for prime time.
Therefore, A. hydrophila AH-3 which lacks a Type III secretion system (T3SS) [29], the strain which lacks polar flagellum [30] and all other mutant strains, excluding the ΔwaaE (O 34 antigen and external core negative strain) [23], were all virulent but to a lesser extent than the A. hydrophila AH-3 WT.
