The phrase "a core defect" is correct and usable in written English.
It can be used to describe a fundamental flaw or issue in a system, product, or process.
Example: "The engineers identified a core defect in the software that caused frequent crashes."
Alternatives: "a fundamental flaw" or "a critical issue".
Despite the complexities of this clinical picture, the pathophysiological defects underlying T2DM can be attributed in large part to a single core defect, that is, inappropriate resistance to the biologic effects of insulin [ 1, 2].
Every Justice wrote an opinion but the core defect of arbitrariness was aptly captured by Justice Potter Stewart's claim that receiving a death sentence was like being struck by lightening.
We suspect that many of these starvation phenotypes are consequences of a core metabolic defect.
The more severe impairments at earlier stages of perceptual processing of complex sounds in PNFA versus semantic dementia are consistent with a core perceptual defect in the cortical processing of complex sound information in PNFA.
These originated surface defect states can act as additional radiative recombination centers and it is also a well-known fact that the presence of surface defect states is always higher in concentration compared to the core defect states [15].
But the core defect is solved not by tweaking the elaborate legal code--such as notoriously rigid "zero tolerance" rules--but by scrapping most legal controls.
It is annotated as phosphomannomutase gene and, because of the severe core defect, we proposed before the name of manBcore [11].
This may potentially be due to the specific environment where priming occurs, some activity of an HCV-derived protein such as core, defects in antigen-presentation, or a liver-specific "tolerance" effect.
This function allows the changes to be visualized as a 2D image of belt core defects on all belt sections and splices.
