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The dynamics of both SAG1 and BAG1 transcript levels suggested a coordinated effect of perturbation of gene expression.
In keeping with a coordinated effect to reduce Wnt signalling, the expression of WNT2 was substantially reduced (7.2-fold vs control; P < 0.05).
Acupuncture has a coordinated effect on a network of cortical and subcortical limbic and paralimbic structures in the human brain [ 43].
Further suggestion that sleep state imparts a coordinated effect on peripheral transcription can be found in noting the similarity in the temporal profiles of the sleep specific transcripts in both tissues.
A well demonstrated effect of dietary FO supplementation in mammals is hypotriglyceridemia, resulting from a coordinated effect of n-3 LC-PUFA in suppressing hepatic lipogenesis and enhancing fatty acid oxidation in liver and muscle [ 18].
The effect of TNFα on expression of Wnt-related genes was less dramatic and did not suggest a coordinated effect on the expression of secreted Wnts and their antagonists.
Similar(51)
Why must you train your brain and neural network to produce a particular coordinated effect or action?
We did so because both SFPQ and CPSF6 are involved in pre-mRNA processing and localized in nuclear paraspeckles [23], which suggests a possible coordinated effect of Snail1.
PSI-miRror captures the concept of coordinated effect of a set of miRNAs over a gene set (as oppose to a set of miRNAs to one gene that is implemented in miRror2.0).
We hypothesised that multiple sites would therefore explain a coordinated regulatory effect on the expression of BLK.
The decreased activity of TH2-CP by Zn2+ may be due to the coordinated effect of the hydroxide ion (ZnOH+) on the catalytic zinc ions (Larsen and Auld 1989).
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