It is a non-invasive drug delivery method which involves electromigration and electroosmosis in addition to diffusion and is shown to be a viable alternative to conventional administration routs such as oral, hypodermic and intravenous injection.
Engineered bacteria can be tailored to deliver drugs, therapeutic proteins, and gene therapy vectors with great efficiency, and with a higher degree of site-specificity than conventional administration regimes.
The G. C. Fontes et al., paper on characterization of alginate and OSA starch bead for the use of controlled release carrier for penicillin is an important finding to alleviate the discomfort of patients undergoing conventional administration of the vital drug.
In major cities such as Kisangani, in the north, conventional administration largely fell away.
However, despite being a powerful biological agent, retinoic acid (RA) is generally not used in regenerative medicine due to its scarce bioavailability via conventional administration.
Hydrogels are used for targeted, controlled, and sustained drug delivery of bioactive agents such as anticancer, antimalaria, antibacterial drugs, etc., resulting in enhanced therapeutic effects when compared to the conventional administration of these drugs [3, 4].
Conventional administration of drugs is mainly based on the systemic delivery of therapeutic molecules, often leading to their non-specific distribution throughout the body, decreasing their efficacy and sometimes resulting in deleterious side effects.
There are many barriers with conventional administration of chemotherapeutic agents such as lack of selectivity, systemic toxicity, poor distribution among cells, limited solubility, inability of drugs to cross cellular barriers, and lack of clinical procedures for overcoming multidrug resistant (MDR) cancer [112, 113].
This therapy is comparable with conventional administration of SIT in the field of efficacy and safety.
This therapy is comparable with conventional administration of SIT in terms of efficacy and safety.
