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Under normoxic conditions a continuous alignment of Cl-5 and ZO-1 could be observed (Fig. 2A, D).
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For each protein sequence (seed), a Smith-Waterman search [ 30] was performed against the aforementioned database to retrieve highly similar proteins with a continuous alignment length of more than 50%% of the query sequence and e-value ≤ 1e-05.
The 3D alignment allows for a continuous alignment through all the states of the recombination.
The continuous alignment of business and IT in a rapidly changing environment is a grand challenge for today's enterprises.
The microscope body tube separates the objective and the eyepiece and assures continuous alignment of the optics.
That highlights the difficulty of continuous alignment of two different systems.
In this paper a new paradigm for next generation enterprise information systems is proposed, which shifts the development approach of model-driven engineering to continuous alignment of business and IT for the agile enterprise.
To annotate the genomic regions linked to the top significant SNPs in this study, each scaffold associated with a filtered RAD tag was annotated using BLASTn (minimum e-value = 1 × 10−20, minimum of 85 bp of continuous alignment (tags are 89 bp after quality-filter).
An example is the 1750 kb stretch of continuous alignment between MTPs 648 {0} and 6844 {1} of RH versus DM in the south euchromatin (Additional file 5: Figure S1).
Identity was confirmed if the tag only produced a significant hit (e-value < 1.0−20, at least 85 bp of continuous alignment) to one scaffold.
In general, achieving that requires a continuous process of organizational alignment.
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