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The phrase "a constructive significance in" is correct and usable in written English.
It can be used when discussing the positive impact or meaningful contribution of something within a specific context.
Example: "The research findings have a constructive significance in improving educational practices."
Alternatives: "a positive impact on" or "a meaningful contribution to".
Exact(1)
The promotion of the soil and water conservation measures for increasing SOC had a constructive significance in the river basin of Loess plateau.
Similar(59)
In fact, the Americans claimed, Lavrov regularly played a constructive role in calming the emotional Zarif.
Shorten said on Friday morning: "Labor will approach this report with a constructive view in mind".
Now it needs to modernise its public services and play a constructive role in Europe.
Community groups need to play a constructive role in this process.
Mr Khader is widely admired these days as a constructive player in inter-religious relations.
Iran has not exactly been a constructive presence in its neighborhood.
Rhythms play a constructive role in respiration, for instance [31, 32].
Kazakhstan has played a constructive role in the country.
A narrative is a constructive format in which a sequence of events is described [ 59].
Having a constructive role in society has been found to be associated with less use.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com