This can be quite a tough constraining influence on how countries regulate drugs (although some countries, such as the Netherlands, have managed to be more flexible, even though they still sign up to the international conventions).
2 4–6 Clinician anxieties about treatment toxicity, side effects and burden may be an important constraining influence on the intensity of cancer treatment offered to older people, 7 8 but other more subtle factors may also influence treatment decisions.
But the frontal lobes also exert an inhibiting or constraining influence on what Pavlov called "the blind force of the subcortex" — the urges and passions that might overwhelm us if left unchecked.
In "Zen and the Art of Motorcycle Maintenance," the narrator sees motorcycles as a noble alternative to the constraining influence of cars: "Because you're used to it, you don't realize that through that car window everything you see is just more TV".
While the sub-glass relaxation was largely unperturbed by the presence of the crystalline phase, both calorimetric and broadband dielectric measurements across the glass transition indicated the existence of a sizeable rigid amorphous phase (RAP) fraction in melt-crystallized PTT owing to the constraining influence of the crystal surfaces over the crystal amorphous interphase region.
(R11) The biggest constraining influence on teaching and learning was the lack of time, amidst a heavy workload of clinical and (for some) managerial duties.
The observed effects could be explained in terms of (i) the different constraining influence of PIA rigid constituents on dynamics in PEA crosslinks, and (ii) the breakdown of motional cooperativity as a result of loosening of PEA chain packing in presence of the PIA rigid nanodomains.
One constraining influence may be the structural motif (beta strand--type II beta turn--beta strand--alpha helix) predicted for the consensus PND sequence by a neural network approach.
Drawing on empirical data from in-depth interviews with fathers across eleven countries, the book shows that the experiences and social processes associated with fathers' home alone leave involve a diversity of trends, revealing both innovations and absence of change, including pluralization as well as the constraining influence of policy, gender, and social context.
However, the antisense mir-431 region in PEG11 showed relaxation of selective constraint perhaps indicating that coiled coil formation in this region can better tolerate amino acid substitutions and is of greater biological importance than the constraining influence of antisense mir-431 in the coding sequence of PEG11.
The constraining influence of the existing political climate is further illustrated when researchers and clinicians were clearly relieved with a change in government (1994): I believe the change in government in 1994/5 when the Christian Democrats were no longer in office, was very important.
