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Together these results show that there is a constant requirement for Treg to maintain B-cell unresponsiveness.
Hence, there is a constant requirement for scientists including bioinformaticians to keep up with the developing technologies and methodologies.
It has a higher antioxidant capacity compared to shorter lived temperate clams, with a constant requirement for stable antioxidant status until old age [ 11, 12].
Taking into account that transcription/translation is not required throughout the full circadian cycle to sustain rhythmicity in Ostreococcus, this study establishes the position of rhythmic targeted protein degradation as not only a central element but also a constant requirement for timekeeping, at least in this organism.
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A second possible mechanism to compute an accumulating or steady signal over time could be the constant requirement for an activated transcription factor to stabilize the transcriptional program or to progress through several stages to finally reach a stable condition.
Despite intensive research efforts towards reaching the required 10% power conversion efficiency (PCE) threshold, the device environmental stability and the constant requirement for high vacuum top metal electrode deposition still remain the major challenges.
Additionally, the transition to digital television is likely to take years, but that does not negate the constant requirement for research and development spending on digital TV chips.
There was a constant demand for results.
Consider an example of a constant demand for water.
An example is the constant requirement of Xist RNA for recruitment of PcG complexes to the Xi (Kohlmaier et al. 2004; Pullirsch et al. 2010; Schoeftner et al. 2006).
However, cellular transformation, by promoting cell cycle progression and cellular growth, would create a requirement for constant supply of fatty acids for synthesis of new cellular membranes, leading to a decrease in substrates for β-oxidation.
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