Exact(2)
Differences in kappa that existed across coder characteristics did not show a consistent direction in favor of any particular coder characteristics, see Figure 2.
Psychosis, HIV, Paralysis and Blood loss anemia were the conditions most often associated with wide variations in kappa across coder characteristics; however these differences in kappa did not show a consistent direction in favor of either high or low volume coders, full-time or part-time coders or hospital site.
Similar(58)
It therefore seems that larger sample sizes are required to clarify the role of non-A-T-causing coding variants in ATM in breast cancer susceptibility, in terms of both variant-specific effects and whether they act in a consistent direction and/or act in a log-additive manner.
Of particular importance in determining the reliability of a model prediction is whether an output response maintains a consistent direction despite noise in measurement data.
There was a gout-protective variant associated in the combined analysis (A-C-T-G-A; OR = 0.80, P = 0.004), with a consistent direction of effect in Polynesians and European Caucasians.
We sought replication of our findings by selecting the highest ranking SNPs with a consistent direction of effect in UK Irish and German cohorts from the GWA discovery stage (P < 1.0E−05).
The chosen SNPs also showed a consistent direction of effect in each of the three case control collections represented by the GENIE Consortium meta-analysed dataset, an international collaboration of three cohorts of type 1 diabetic patients discordant for DN totalling 2916 with nephropathy and 3315 without nephropathy [ 22].
If this process happens to occur in a consistent direction—say, the largest individuals in each generation tend to leave more offspring than smaller individuals then there can be a gradual, generation-by-generation change in the proportion of traits in the population.
The strategy of using multiple measures and searching for a consistent direction of connectivity changes in AD across the methods has the advantage of increasing knowledge on the behavior, such as sensitivity, specificity, availability, and applicability, of the different measures relative to each other.
A 1-2‰ difference between the δ13C values was evident between the two leaves in each biochemical fraction, in a consistent direction (dwarf > tall).
The most intuitive explanation for why a majority of lineages in a group would evolve in a consistent direction (i.e., exhibit a driven trend) is that this change is adaptive in other words, that it is the result of directional natural selection operating among individual organisms within populations of various species.
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