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Meta-analyses of prognostic markers have been facilitated when individual patient data were available (Look et al, 2002), in particular to determine a consistent cutoff level (Sakamoto et al, 1996).
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ORFs with a bad ranking value (arbitrary but consistent cutoff for all comparisons) for any two of these three parameters were considered as false positives and discarded.
Better quality studies are needed to address the utility of CRP testing for pediatric infections and to define a consistent optimal cutoff value that can discriminate bacterial from viral infections or other diseases.
Although we assume that most laboratories used immunohistochemistry assays and consistent cutoff points, it is possible that some laboratories used different methods or different cutoff points.
Therefore, across studies reported so far, in more than 2,000 patients, there appears to be a consistent ischemic iFR cutoff of 0.85 to 0.86, which matches an FFR 0.75, and a clinical iFR cutoff of iFR 0.89 to 0.90, which provides the best agreement with the clinically used FFR of 0.80.
The composite membranes also showed a consistent molecular weight cutoff trend with both positively and negatively charged dyes (Fig. 5e and Supplementary Fig. 27).
In this study, 1,971 of 1,988 samples (99.1%) received a clinical interpretation for all three chromosomes based on a consistent z-score cutoff of 3.0.
Next, we compared characteristics of girls with hormone measurements by inhibin B concentrations dichotomized as being below or above an a priori determined cutoff consistent with puberty (> 35 pg/mL) (Crofton et al. 2002; Sehested et al. 2000; Teilmann et al. 2007).
have a consistent approach.
We chose a cutoff of FDR <0.05, with p < 1 × 10 5 and a minimum fold change of 1.3, to capture genes with a consistent change between groups.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com