Convention organizers knew Khan would be a powerful speaker, but they had not expected he would be a considerably more potent symbol for the campaign than the other "everyday Americans" invited to the stage — and everyone else who appeared in Philadelphia.
The Y516F mutation causes similar changes in the guanine nucleotide binding and transamidating activity characteristics of the protein as R580A, although the latter mutation is a considerably more potent mutation than the former.
We classified BPA and its derivatives into the four groups, depending on their receptor binding affinity for ERR-γ : that is, group A, BPA and chemicals as potent as BPA; group B, chemicals considerably potent; group C, chemicals moderately potent; and group D, inactive chemicals.
When the benzene B-ring of 4-α-cumylphenol was substituted with either methyl or ethyl, the resulting 4- tert-butylphenol [HO-C6H4-C CH3 2-CH3] and 4- tert-amylphenol [HO-C6H4-C CH3 2-CH3]H3] were considerandy potent, with values of 26.1 nM and 33.2 nM, respectively (Table 2).
Many of the considerably potent inhibitors of baker's yeast α-glucosidase possessed lower inhibitory activities against mammalian α-glucosidase and is suggested to be due to the difference of molecular recognition in the binding site of the enzyme [ 49, 50].
1,12-Diazadibenzo a,i)pyrene (I), an isostere of the extremely potent carcinogen dibenzo(a,i)pyrene, also displays carcinogenicity although to a considerably lesser degree than the latter compound.
The Groovy ($14) looks like a benign limeade but is considerably more potent; it's made with shiso-infused vodka and yuzu juice and is topped with a shiso leaf, a member of the mint family that adds a nice lilt to the drink.
That's still considerably less potent than an estimate from Russia's defense minister Sergei Ivanov, who asserted yesterday that the blast equaled 5 to 15 kilotons of TNT.
The results indicated that aflatoxin M1 is an hepatic carcinogen although it is considerably less potent that aflatoxin B1.
Furthermore, in in vitro models of angiogenesis, 2-MeOE2 bisMATE proved to be considerably more potent as an inhibitor of angiogenesis than 2-MeOE2 (Netmal et al, 2004).
Like several other responses of neurons to estrogen (Green et al. 1997; Levin-Allerhand et al. 2002; Yu et al. 2004), PSSD is sensitive to both the 17α and 17β isomers of estradiol, the 17α isomer being considerably more potent as an inducer of CA1 spine synapses (MacLusky et al. 2005), despite the fact that it has very low uterotrophic activity (Lundeen et al. 1997).
