Exact(1)
APJ expression was previously shown reduced in renal arteries of db/db mice by western blot [66], but we show here, by microarray analysis of purified glomerular endothelial cells, and by immunohistochemistry of glomeruli (see below), that there is actually a considerably elevated level of APJ specifically within the endothelial cells of the glomerulus.
Similar(59)
Thus, if the level of serum antibodies was normalized to the number of B lymphocytes present in the spleen, i.e. cells with the potential to secrete pathogen specific antibody, the perinatal lethal mice had considerably elevated levels of circulating IgM and IgG compared to wild type, Tg, and KO mice, consistent with an ongoing infection (Fig. 7C, D).
HFD-fed rats exhibited considerably elevated levels of serum ALT, AST and ALP.
In this report, we found that type 1 VHL mutants had considerably elevated levels of HIF-2α.
In 2010, Fitzpatrick et al.[ 84] demonstrated that children with biopsy-proven NAFLD also showed considerably elevated levels of these cytokeratin 18 fragments when compared with healthy controls.
RT-qPCR confirmed a considerably elevated transcript level of err1 in the recombinant strain compared to the parental strain, which was already observed during the above-mentioned screening process (Figure 3a).
Our patient had a considerably elevated FGF23 level with consequent renal phosphate wasting.
Accordingly, these participants have a considerably elevated risk of morbidity and mortality.
A considerably elevated GFAP expression is evident in animals injected with A β1-42 (right panel, Figure 1(b)).
In addition, both RT-PCR and immunoblotting showed that killing the parasite with BW720c considerably elevated the level of TLR4 mRNA and protein (Fig 5B and C).
Iron deficiency leads to increased erythroblast numbers and increased TfR expression and thus to considerably elevated sTfR levels.
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