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The phrase "a considerable variation in" is correct and usable in written English.
You can use it when discussing differences or changes in a particular context, such as data, opinions, or characteristics.
Example: "The study revealed a considerable variation in the results across different demographics."
Alternatives: "a significant difference in" or "a notable discrepancy in".
Exact(60)
It is true, of course, that there is a considerable variation in the sensitivity of human skins; the owners of a tender hide must go more warily than those more coarsely covered.
Zooflagellates exhibit a considerable variation in form, and they may be free-living, symbiotic, commensal, or parasitic in humans and other animals and in certain plants.
We can see that all benchmarks show a considerable variation in execution times of tasks.
A considerable variation in the uptake of [18F]EF5 was also detected between the two scans.
Generally, a considerable variation in antioxidant activities and phytochemical contents was observed between the cereals.
The boxplot illustration (Fig. 7d) reveals a considerable variation in median annuity differences on the municipality level.
The relationship between interestingness for fans and other users indicates a considerable variation in how widely stories appeal to the general user community.
There is a considerable variation in transfer practices among centers and countries, which may explain the differences in outcomes observed in different studies.
While there is a considerable variation in detail, spatial filtering models for symmetry perception share many features.
In summary, results from this study demonstrate a considerable variation in outcrossing rates and genetic diversity among weedy rice populations from a given geographical range.
A considerable variation in total nucleic acid content of urine has been previously documented, for example, 27 189 ng/ml [28], 50 200 ng/ml [18].
More suggestions(15)
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a major variation in
a considerable divergence in
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a vast variation in
a considerable swing in
a large variation in
a big variation in
a considerable deviation in
a noticeable variation in
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a tremendous variation in
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a considerable interest in
a considerable uptick in
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com