The phrase "a considerable problem in" is correct and usable in written English.
It can be used when discussing a significant issue or challenge within a specific context or field.
Example: "The lack of funding has become a considerable problem in the development of new technologies."
Alternatives: "a significant issue in" or "a major challenge in".
Lameness poses a considerable problem in modern dairy farming.
Diseases carried by mosquitoes and ticks are also a considerable problem in the United States.
Suture hole bleeding is a considerable problem in vascular procedures using polytetrafluoroethylene (PTFE) grafts.
While the bulk of the state's homeless population is in New York City, homelessness is a considerable problem in the rest of the state.
The technical difficulties related to the insertion of a long intestinal tube into the jejunum under fluoroscopy present a considerable problem in patients with an intestinal obstruction.
Audibility is a considerable problem in the opening scenes, and you need to concentrate hard to figure out who is who, but by the time a dodgy pre-show sandwich forced me to exit the theatre 10 minutes before the end, this low-key show had exerted a quiet grip.
First, Occlusion, whereby your body blocks the camera sensors from gathering the signal dispatched by the Touch controllers, is a considerable problem if your sensors are only in front of you and when tracking drops it really messes with immersion.
The continued Allied presence in Malta was a considerable problem for Rommel in Africa, who was losing as much as ⅓ of his supplies from Italy to submarines and bombers based there.
In particular, humic acids pose a considerable problem and will interfere in enzymatic manipulations of DNA (5, 14, 16).
We have a considerable problem with the manner in which we are fed news of death, bloodshed and killings.
Due to the substantial flexibility and extended shape of the core Mediator structure, the cryo images showed a very low signal-to-noise ratio and could not be stably aligned, leading to a considerable problem of model bias in the previous cryo reconstruction of the Mediator complex.
