The phrase "a considerable problem and" is correct and usable in written English.
It can be used when discussing an issue that is significant or substantial, often leading into further explanation or elaboration.
Example: "The project faced a considerable problem and required immediate attention to avoid delays."
Alternatives: "a significant issue and" or "a major concern and".
Since 1915, food waste has been identified as a considerable problem and has been the subject of ongoing media attention, intensifying with the launch of the "Love Food, Hate Waste" campaign in 2007.
Morbidity in asthma is a considerable problem, and is mainly related to the more severe phenotypes of the disease.
In particular, humic acids pose a considerable problem and will interfere in enzymatic manipulations of DNA (5, 14, 16).
Moreover, its ability to acquire and/or maintain antibiotic resistance genes has become a considerable problem and an obstacle to successful therapeutic treatment [ 4, 5].
Non-adherence to oral anticoagulation (OAC) seems to be a considerable problem and leads to an increase in adverse medical events, including stroke and bleeding events [ 41].
Therefore, we had held that this confusion between groups without sufficient presentation is a considerable problem, and set up a protocol to separate subjects on waitlists from those undergoing TAU.
Botanists also study weeds, which are a considerable problem in agriculture, and the biology and control of plant pathogens in agriculture and natural ecosystems.
The presence of multiple close allergen homologues across the fungal kingdom carrying epitope orthologues that are structurally indistinguishable from IgE binding epitopes may raise a considerable problem in diagnosis and classification of fungal allergy.
Fraudulent transactions occurring via the Internet or Automatic Teller Machines (ATMs) present a considerable problem for financial institutions and consumers alike.
However, interlaboratory differences in the results of HER2 testing are still a considerable problem in gastric cancer, and one cause may be inappropriate preparation of formalin-fixed paraffin-embedded tissues.
Despite numerous initiatives to improve the working environment for nursing aides, musculoskeletal disorders (pain) is still a considerable problem because of the prevalence, and pervasive consequences on the individual, the workplace and the society.
