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This is clearly a considerable oversimplification since there is no allowance for the differences in risks between BRCA1 and BRCA2 carriers (Ford et al, 1998; Malone et al, 2000; Antoniou et al, 2003) or for other lower risk genes.
This is a considerable oversimplification, given the interacting roles of other hormones such as estrogens, arginine vasopressin, and cortisol (e.g., van Anders et al. 2011), but it serves as a useful and pragmatic first step in developing the connections of endocrine adaptations with the genetics, and epigenetics, of human risks and manifestations of disease.
Similar(58)
His affair with Héloise and his consequent castration are the stuff of legend, and his controversy with the much more traditional Bernard of Clairvaux (1090 1153) has only enhanced his reputation among those who have viewed him (with considerable oversimplification) as a champion of reason over authority.
That is a considerable understatement.
But a considerable challenge remains.
A considerable Internet furor ensued.
Malaysia produces a considerable volume.
Ashley Williams proved a considerable barrier.
It's a considerable impact.
It's a considerable headache.
It's a considerable success.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com