In contrast to thymidine nucleosides, cytosine derivatives cause considerable obstacles when reacted with chlorophosphane 172: for instance, cycloSal modifications of 3TC or ddC were achieved in very low yields.
This level is considerably higher than is found in oral contraceptives, and this is a considerable obstacle that must be overcome when considering treatment of very young women.
Family disagreements, she said, are a considerable obstacle.
This is a considerable obstacle for stem-cell treatments that aim to replace retinal neurons.
After beating Canada Sampson even made a passing reference to Sir Alf Ramsey and 1966 but Japan will present a considerable obstacle.
That is a considerable obstacle, given that it was the upper house that posed the real challenge in terms of governability.
The only snag from the point of view of Liverpool, United, Spurs and Chelsea is that City will form a considerable obstacle in Europe too.
A considerable obstacle to understanding contemporary philosophical usage of the term, however, is that the notion does not seem to be a unitary one.
The highly distributed and non-transparent nature of cloud computing represents a considerable obstacle to the acceptance and market success of cloud services.
But getting the toxic materials out of Syria amid a raging civil war has been a considerable obstacle.
But getting the toxic materials out of Syria amid a raging civil war has been a considerable obstacle. .
