Since the criteria for this study include disease conditions, and further good compliance to the vitamin protocol, we expect considerable healthy volunteer effect in this study including but probably not limited to the type of bias we are studying.
In contrast, our analysis shows that there is a considerable variability among healthy donors in percentage of receptor-positive NK cells and in magnitude of expression (Figures 2, 3).
Hormone assays performed at the end of the study revealed that a considerable portion of the healthy elderly men in our sample met criteria for hypogonadism and suggests that their low hormone levels may have mitigated against discovering other significant hormone cognition relationships.
Overall, in all symptom-defined disorders (including overactive bladder), defining very mild/rare symptoms as pathological blurs the distinction between mild and severe, causing a considerable risk of encouraging healthy people to perceive themselves as sick [25].
Yet, this is not the case for p. (R1389H), which is present at a considerable frequency in our healthy controls and all publicly available databases (∼0.1 0.3%).
We did not perform an extensive epimutation screen in controls, because a considerable percentage of apparently healthy women may develop BC or OC during lifetime, and even in our affected patient cohort, the number of suspect (≥6%) promoter methylation values was relatively low (13/641; 2%).
Intact stomachs of 2-day-old, well-fed mice and rats examined by Head et al. [9] showed a considerable number of intact and healthy cells dispersed in the whey clot.
Interestingly, in this study comparison of plasma VEGF concentrations between overweight subjects with a metabolic syndrome and a considerable number of normal weight healthy controls did not reach significance which casted some doubt on a direct relationship between circulating VEGF and BMI; a result which can probably be explained by the inhomogeneity of the included subject groups.
In the healthy population, a considerable variation in GC sensitivity has been demonstrated by low-dose (0.25 mg) dexamethasone suppression tests and functional in vitro assays [ 21, 22].
In healthy subjects, a considerable part of the postprandial insulin response is due to the actions of the incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).
Professional football players mostly healthy athletes consume a considerable quantity of medication, especially non-steroidal anti-inflammatory drugs, prior to competition.
