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The phrase "a considerable frequency in" is correct and usable in written English.
It can be used when discussing the occurrence or prevalence of something within a specific context or area.
Example: "The study revealed a considerable frequency in the occurrence of the rare disease among the population."
Alternatives: "a significant occurrence in" or "a high prevalence in".
Exact(2)
This latter scenario may be far more frequent and even small ORs would still be important to identify for variants that have a considerable frequency in the population.
Yet, this is not the case for p. (R1389H), which is present at a considerable frequency in our healthy controls and all publicly available databases (∼0.1 0.3%).
Similar(58)
We use these error probabilities to ensure that in the experiments, participants are exposed to errors at a considerable frequency.
A change of aspartic acid (D) to glycine (G) at position 222 in the haemagglutinin (HA) protein of pandemic influenza A (H1N1) 2009 viruses was described in Norway on November 2009 with considerable frequency in fatal and severe cases.
The LV false tendons are seen with considerable frequency in the echocardiographic evaluation of patients referred for having clinically innocent heart murmurs.
The book remains relevant more than 200 years after it was written, in large part because arguments very similar to Paley's underlie current challenges to the teaching of evolution (indeed, his name arises with considerable frequency in associated discussions).
Based on the usually weak and transient interaction between kinases and their substrates, it is not expected that this type of interaction appear with considerable frequency in yeast two-hybrid screens.
Both missense point mutations and large extracellular domain deletions (EGFRvIII, which due to alternative splicing misses exon 2 7) affecting the EGFR gene have been reported at considerable frequency in GBM and result in constitutive activation of the receptor and of the underlying PI3K pathway [12].
Owing both to their considerable frequency in the infertile population and ambiguous clinical significance, partial AZFc deletions are the most intensely debated AZFc variants.
In several major human cancers, the WNT/ β-catenin signal transduction pathway is constitutively activated, regularly in colon carcinoma and hepatoma, and with considerable frequency in melanoma, mammary carcinoma, medulloblastoma and in some cases of renal, ovarian, thyroid and prostate carcinomas (Polakis, 2000).
Indeed, TLR5392STOP is a non-functional allele that may reach considerable frequencies in some human populations (up to 23%; [ 65]) despite increasing the susceptibility to the Legionnaires' disease.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com