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In humans, endothelial repair and blood vessel formation are mainly performed by circulating endothelial progenitor cells (EPCs) characterized by a considerable expression of vascular endothelial growth factor receptor 2 (VEGFR2), CD34, and CD133, pronounced tube formation activity in vitro, and strong reendothelialization or neovascularization capacity in vivo.
Differentiation and matrix mineralization in vitro involve a considerable expression of genes as well as protein production, leading to the mineralization.
The detection of such a considerable expression of cell membrane bound or derived PrPC in milk constitutes one of the key requirements for the generation of infectious prions in the udder of infected animals.
For example Tek, also known as Tie2, showed expression levels of about 3,000 in the glomerular endothelial cells, but also a considerable expression level of about 1,000 in mesangial cells.
The reason for a considerable expression of LDH-5 outside hypoxic areas could be the high rate of aerobe glycolysis (the Warburg effect) as often observed in malignant tumors[ 4], although alternative explanations are possible, as pyruvate can originate from other pathways as well[ 23].
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Comparative proteomic analysis demonstrated a considerable proteome expression difference between Jimai 20 and Zhoumai 16 during grain development.
In Hs578TEpCAM cells, overexpression was accompanied by a considerable decreased expression of the Wnt pathway inhibitor SFRP1, by an increased proliferation rate and enhanced sensitivity to Docetaxel.
"There has been considerable expression of concern and opposition to that particular portion of the proposal".
Importantly, we discovered considerable expression of PDE8A in these cells (Fig. 5A).
Conversely, considerable expression differences were reported in other tissues, including testis.
Enterocytes displayed considerable expression of glyco-epitopes that bound exogenous rGal-1.
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