Sentence examples for a considerable drawback when from inspiring English sources

The phrase "a considerable drawback when" is correct and usable in written English.
It can be used to introduce a negative aspect or limitation associated with a particular situation or condition.
Example: "The lack of proper training can be a considerable drawback when trying to implement new software in the workplace."
Alternatives: "a significant disadvantage when" or "a major limitation when".

Exact(1)

More importantly, the pipeline filtered out SNPs that did not belong to the same exon by using the draft genome sequence for E. grandis, therefore avoiding failures due to SNP located in intron/exon junctions, a considerable drawback when developing SNPs from ESTs [ 51].

Similar(59)

Opioid analgesic tolerance remains a considerable drawback to chronic pain management.

While the arguments mentioned above reduce this problem, it remains a considerable drawback to some experimental evidence.

The need for the reference video or for partial information about it is a considerable drawback in many real-time applications.

Forcing of engines together with positive properties – uprating within 5 50%% has a considerable drawback, i.e. the decrease of its service reliability.

However, a considerable drawback in using optimisation to estimate parameters for complex models is that multiple parameter sets may "fit" the data equally [1], [17].

High FP rate is still a considerable drawback of CAD.

This is a considerable drawback, given that VAT and not SAT plays a decisive role in the genesis of cardiovascular sequelae (9, 11– 11).

The 1GB of memory is a big drawback when running Windows and Microsoft Office.

This is a drawback when assembly conditions have to be optimized against a negative control.

But he can't convert present experience into memory, which is a drawback when plotting his revenge.

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