Sentence examples for a considerable drawback to from inspiring English sources

Opioid analgesic tolerance remains a considerable drawback to chronic pain management.

While the arguments mentioned above reduce this problem, it remains a considerable drawback to some experimental evidence.

However, a considerable drawback in using optimisation to estimate parameters for complex models is that multiple parameter sets may "fit" the data equally [1], [17].

More importantly, the pipeline filtered out SNPs that did not belong to the same exon by using the draft genome sequence for E. grandis, therefore avoiding failures due to SNP located in intron/exon junctions, a considerable drawback when developing SNPs from ESTs [ 51].

The need for the reference video or for partial information about it is a considerable drawback in many real-time applications.

Forcing of engines together with positive properties – uprating within 5 50%% has a considerable drawback, i.e. the decrease of its service reliability.

However, this algorithm has a considerable drawback in noisy environments and the membership degrees are computed using only the grey levels and do not take into account the spatial information of pixels with respect to one other.

Graphene [2 5] is the most well-known member in the family of 2D materials, but its gapless band structure has been deemed as a considerable drawback for realizing switching operation, which is essential for digital logic devices.

High FP rate is still a considerable drawback of CAD.

This is a considerable drawback, given that VAT and not SAT plays a decisive role in the genesis of cardiovascular sequelae (9, 11– 11).

But there are considerable drawbacks to this part of the plan too.