Opioid analgesic tolerance remains a considerable drawback to chronic pain management.
While the arguments mentioned above reduce this problem, it remains a considerable drawback to some experimental evidence.
Graphene [2 5] is the most well-known member in the family of 2D materials, but its gapless band structure has been deemed as a considerable drawback for realizing switching operation, which is essential for digital logic devices.
Forcing of engines together with positive properties – uprating within 5 50%% has a considerable drawback, i.e. the decrease of its service reliability.
This is a considerable drawback, given that VAT and not SAT plays a decisive role in the genesis of cardiovascular sequelae (9, 11– 11).
However, this algorithm has a considerable drawback in noisy environments and the membership degrees are computed using only the grey levels and do not take into account the spatial information of pixels with respect to one other.
However, a considerable drawback in using optimisation to estimate parameters for complex models is that multiple parameter sets may "fit" the data equally [1], [17].
For widespread lesions, however, current endoscopic treatment modalities (eg, endoscopic resection, argon plasma coagulation, photodynamic therapy) are associated with considerable drawbacks, of which esophageal stricturing is the most significant.
The most considerable drawback represents controlling and optimizing the quality of the CNT/metal contact.
A considerable sleight-of-hand.
