Sentence examples for a considerable disadvantage of from inspiring English sources

A considerable disadvantage of boosting in adolescence is that there is currently no infrastructure for routine vaccination in this age group, particularly in the developing world.

A considerable disadvantage of intraspecific calibrations is that they will often produce date estimates with a larger degree of uncertainty than those made using external calibrations.

A considerable disadvantage of classical Schistosoma diagnostics is the persistence of serologic markers and egg shedding after successful treatment.

However, the time and cost related to the downstream analysis of the data generated by RNA-seq is a considerable disadvantage of this approach.

A considerable disadvantage of manual volume correction is the significantly higher measurement time, which has been demonstrated in this study and is in agreement with human studies (15, 17).

However, a considerable disadvantage of this method is the somewhat cumbersome work-up of the aqueous reaction mixture in order to isolate the product for its further use [ 146].

A large arboreal primate without entirely prehensile hands is at a considerable disadvantage in moving about in the canopy of trees, but a small one suffers little disadvantage.

Although water is clearly an attractive lubricant for economical, ecological, thermal management and other reasons, it suffers from a considerable disadvantage compared to oil, namely its low pressure-coefficient of viscosity, which has serious consequences for elastohydrodynamic lubrication.

While everyone lauds transparency and accessibility, the blanket rubric puts all the kids in my group -- regardless of actual circumstance -- at a considerable disadvantage.

Of course, women have always been at a considerable disadvantage in electoral politics.

A child who has deficits in either of these skills could, depending on their severity, be at a considerable disadvantage in the classroom and at substantial educational risk.