The phrase "a considerable difference of" is correct and usable in written English.
It can be used when discussing a significant disparity or variation between two or more items, concepts, or situations.
Example: "There is a considerable difference of opinion among the experts regarding the best approach to climate change."
Alternatives: "a significant difference in" or "a notable difference between".
Three is a considerable difference of opinion as to the exact meaning of this phrase.
There is a considerable difference of the uptake of Mn among 50, 75 and 100%% sludge plants.
A considerable difference of these values allows to suppose that controlling temperature in the measuring flow cell one can discriminate these completely and partially complementary oligonucleotides.
The research presented in this paper has analyzed 50 years of urban evolution in Italy and noted a considerable difference of geographic patterns of settlement growth compared to other countries of the World.
In the present study, the ewes were either milked once or twice a day over the lactation, leading to a considerable difference of the shape of the lactation curves and total milk yields.
The pull-off force for AR 4.0 samples are similar for the two testing velocities of 20 and 60 μm s−1, but a considerable difference of at least a factor 2 was found for the AR 4.5 and AR 5.0 samples.
However, there is a considerable difference on the MAF of pKF3-70 and pKF3-140 between S1 and S2.
Thus, the timing and length of BrdU administration can make a considerable difference to the number of labeled cells.
Our sense of the ultimate values that private ownership is supposed to serve may make a considerable difference to our interpretation of the takings clause and other doctrines.
Since game theory is about economically rational action given the strategically significant actions of others, it should not surprise you to be told that what agents in games believe, or fail to believe, about each others' actions makes a considerable difference to the logic of our analyses, as we will see.
The detection limit makes a considerable difference to the number of patients in whom C-peptide was detected (Fig. 1).
