The phrase "a considerable deficiency" is correct and usable in written English.
It can be used to describe a significant lack or shortfall in something, often in a formal or academic context.
Example: "The report highlighted a considerable deficiency in the company's safety protocols, which needed immediate attention."
Alternatives: "a significant shortcoming" or "a notable lack".
In other words, studies with low validity – if they are not excluded by the authors of meta-analyses due to considerable deficiencies – influence the result of a meta-analysis to the same degree as valid studies.
After a charming apartment that was close to the beach but way too small, and a house whose breathtaking view did not outweigh its considerable deficiencies and not-so-charming landlord, we found The One.
Generally, we may say that the quality of the elderly's housing and local surroundings in Germany displays considerable deficiencies and in many cases is unsuitable for older people.
An external audit conducted in such clinics in Cape Town demonstrated considerable deficiencies in the quality of care provided (2).
We critically analysed 26 tools that aimed to support decision making or patient understanding in the treatment of acute stroke with thrombolysis, and the majority demonstrated considerable deficiencies.
While ACS has excellent biocompatibility and did not interfere with AMOR in previous studies, its mechanical properties and rapid resorption are considerable deficiencies.
Micronutrient deficiencies pose a considerable threat to independence and longevity, because they are related to several adverse functional outcomes.
The "Dopamine Deficiency Hypothesis" and a considerable number of recent pharmacological studies propose to thoroughly verify and improve the standard of knowledge regarding a possible role of dopamine in the pathogenesis and treatment of depression.
Reduction of IDEF2 transcript abundance by RNAi under conditions of Fe deficiency resulted in a considerable reduction in transcript abundance of the Fe-phytosiderophore transporter OsYSL2.
The GOA consortium is making a considerable and timely effort to rectify these deficiencies and some improvement has already been made.
