Sentence examples for a considerable defect in from inspiring English sources

The phrase "a considerable defect in" is correct and usable in written English.
It can be used to describe a significant flaw or shortcoming in something, such as a product, system, or argument.
Example: "The report highlighted a considerable defect in the software that could lead to data loss."
Alternatives: "a significant flaw in" or "a major issue with".

Exact(1)

Morphological analysis of sections showed a mild dilatation of the lateral ventricles and a more prominent dilatation of the third ventricle, with a considerable defect in choroid plexus (CP) morphology (Figure 5D K, n = 5).

Similar(59)

DOI: http://dx.doi.org/10.7554/eLife.09073.019 We also examined glcs bearing a pygo null allele (Thompson et al., 2002), which revealed considerable defects in Eve and Ubx expression, and almost complete absence of Wg, as previously reported for a different null pygo allele (Parker et al., 2002).

Furthermore, there were considerable defects in p24 CA release, in particular in the case of rodent cells.

Premature expression of these mRNAs leads to considerable defects in development [ 12, 13].

Fly mutants lacking akirin had considerable defects in muscle mass and morphology [ 32].

Hence, although breeding Vangl2 Lp, Scrib Crc and Celsr1 Crsh onto the C3H/HeH background increases the penetrance of craniorachischisis in double heterozygotes, there remains a considerable difference in defect penetrance between the different intercrosses.

In both media, the Δ parABc strain did not display a considerable growth defect.

eco1Δ wpl1Δ cells by themselves display a considerable cohesion defect (Ben-Shahar et al. 2008).

The large magnitude of dark current density indicates that there are considerable defects and dislocations in the ZnO film grown on a Si substrate, which is a typical result of heteroepitaxy between largely mismatched materials [25].

Reduction by ring-opening of epoxide group by hydrazine treatment seemed to restore the sp2 network, while thermal annealing left a considerable number of defects in the graphene sheet through the formation of volatile gases.

We conclude that breast carcinomas from MMR gene mutation carriers conformed to other LS tumors in that IHC analysis of MMR protein expression was more sensitive than MSI analysis to detect a MMR defect but deviated from the remaining tumors in that even IHC failed to detect a MMR defect in a considerable proportion (35%) arguing against biallelic inactivation in those cases.

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